hrp0086fc9.6 | Pathophysiology of Disorders of Insulin Secretion | ESPE2016

Circulating Angiopoietin-2 Levels in Young Patients with Type 1 Diabetes Mellitus: A Link between Inflammation, Micro-Vascular Complications and Subclinical Atherosclerosis

Elbarbary Nancy , El-Asrar Mohamed Abo , Ismail Eman , Bakr Al Shaimaa

Background: Angiopoietin-2 is a growth factor involved in the pathophysiology of different vascular and inflammatory diseases such as arteriosclerosis. Carotid or aortic scans provide non-invasive screening tools for assessment of preclinical atherosclerosis in high-risk children.Aim: We assessed serum angiopoietin-2 in children and adolescents with type 1 diabetes mellitus as a potential marker for diabetic vascular complications in relation to glycemic...